The Triprenylated Anthranoid Ferruginin A, a Promising Scaffold for the Development of Novel Antibiotics against Gram-Positive Bacteria
A unique high-diversity natural product collection as a reservoir of new therapeutic leads
Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors
Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells
Structural Elucidation and Antimicrobial Characterization of Novel Diterpenoids from Fabiana densa var. ramulosa
The Revaluation of Plant-Derived Terpenes to Fight Antibiotic-Resistant Infections
Alvaxanthone, a Thymidylate Synthase Inhibitor with Nematocidal and Tumoricidal Activities
Cannabis sativa L. Inflorescences from Monoecious Cultivars Grown in Central Italy: An Untargeted Chemical Characterization from Early Flowering to Ripening
The Pictet-Spengler Reaction Updates Its Habits
ent-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors
A novel colistin adjuvant identified by virtual screening for ArnT inhibitors
Nigritanine as a New Potential Antimicrobial Alkaloid for the Treatment of Staphylococcus aureus-Induced Infections
A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth
Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T‐cell Acute Lymphoblastic Leukemia
In Memory of Maurizio Botta: His Contribution to the Development of Computer-Aided Drug Design
H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma
Olefin Metathesis Reaction as a Locking Tool for Macrocycles and Mechanomolecules Construction
Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61
First Detection of a Ruthenium–Carbene–Resorc[4]arene Complex During the Progress of a Metathesis Reaction
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors
